Showing posts with label The Sleep. Show all posts
Showing posts with label The Sleep. Show all posts

The Necessity of Sleep

 By Homar N. Murillo

Sleep is one of the most investigated subjects in neuroscience and psychology but it is also the least understood in terms of mechanism and functions. However, it is clear that sleep is an important biological need of complex organisms. There seems to be a correlation between brain complexity and the hours needed for sleep.

Among vertebrates, mammals have the longest hours of sleep. The number of hours tends to drop as the organism becomes much simpler. For instance, most fish species hardly need to sleep. They only need to sleep one hemisphere of their brain at a time. This is especially true for sharks which do not have swim bladders. Hence, they need to swim all the time in order to avoid sinking at the bottom of the sea.

On the other hand, humans have complex brains that require an average of eight hours of full sleep. This means that both hemispheres of the brain must be rested and temporarily isolated from environmental stimuli. However, mere rest and isolation from stimuli are insufficient. A complete sleep must also have dream component. A dreamless sleep or a coma-like sleep does not have the same rejuvenating effect as a sleep with dream component. Dreaming occurs during the rapid eye movement (REM) cycle.

Patients who suffer from insomnia and induced sleep deprivation typically experience a wide range of psychological and physiological problems. These include hallucinations, irritability, hypertension, loss of focus, heart disease and weakened immune system. Prolonged sleep deprivation such as in the case of chronic insomnia can lead to death. Sleeping pills do not help in the long run. They may actually worsen the situation.

Complete sleep apparently has the function of allowing the brain synapses to organize and consolidate memories and new learning. It also helps in removing garbage information, thereby preventing information overload. People who are deprived of sleep have slower learning ability. They also tend to be less socially adaptable.

Based on research, sleep also has crucial role in maintaining hormonal balance, regulating temperature and maintaining normal heart rate. People who do not have sufficient sleep have the tendency to have abnormal metabolic functions because of hormonal imbalance.

Some of the hormones that are closely associated with the sleep-wake cycle are melatonin, cortisol, and thyroid stimulating hormone (TSH). Melatonin directly regulates sleep. Cortisol is a stress hormone which is primarily responsible for increasing blood sugar level. It also aid in metabolizing fat, protein and carbohydrate. TSH is responsible for stimulating the thyroid gland to produce thyroxine (T4), and then triiodothyronine (T3) which is crucial in metabolic processes in almost every tissue in the body. Sleep also has direct role in normal growth. The normal production of prolactin and growth hormone is critically determined by normal sleep.

Article Source: http://EzineArticles.com/

The Basic Mechanism of Sleep

 By Homar N. Murillo

Sleep is a natural process that is regulated by the cycle of day and night. The mechanism of sleep is not yet fully understood. The need for it, however, is correlated with physiological and psychological rejuvenation. Humans evolved the need for sleep in synched with the cycle of daylight and night time darkness. Falling asleep involves a cascade of chemicals in the brain that commences as darkness falls and the temperature of the surrounding drops. This cycle typically determines the circadian

Circadian rhythm
Most people have circadian rhythms that are synchronized with the local day and night cycle. This synchronization can be upset by self-imposed sleep deprivation, drinking coffee or any caffeinated drinks, drinking alcoholic beverages, eating too much or by travelling to another time zone in an airplane. The latter is referred to as jet lag. It is a condition wherein the circadian rhythm of a person is still in synch with the time zone from where he or she originated. Hence, the circadian rhythm conflicts with the actual night-day cycle of the locality.

When the sun begins to set, a series of neuro-electrical and chemical reactions begins in the brain. It starts with the senses, particularly involving the visual, tactile and thermo-regulatory perceptions. All of these cues are centrally processed in the hypothalamus.

Melatonin production
The suprachiasmatic nucleus receives signals from the hypothalamus which is then relayed to the pineal gland. In turn, the pineal gland gradually releases the sleep hormone, melatonin, into the blood stream.

Melatonin has the effect of slowing the heartbeat, relaxing the muscles and triggering sleepiness. Melatonin in the blood stream usually last for about twelve hours from around 9:00 p.m. to 9:00 a.m. Normal sleep patterns typically occur in two major parts, namely, the non-REM (rapid eye movement) sleep and the REM sleep.

NREM and REM components
The non-REM is consists of three stages that are distinguishable based on the brainwave patterns as detected and measured by a hypnogram. The non-REM stages are as follow:

NREM stage 1: This is the twilight zone of sleep, the narrow gap between sleepiness and wakefulness. The muscles are still active but the eyes are rolling and the eyelids are moderately closing and opening. A sleeper may still be easily awaken and partially conscious.

NREM stage 2: This stage is marked by the theta wave brain pattern. A sleeper may already be hard to awaken during this stage. The alpha waves of the initial stage are abruptly interrupted. The abrupt interruption is known as sleep spindles and K-complexes.

NREM stage 3: It is during this stage that slow-wave sleep (SWS) begins. The SWS starts in the preoptic area and it is distinguishable by delta wave activity, high amplitude waves at less than 3.5 Hertz. A sleeper will not anymore be responsive to non-intense environmental stimuli.

After the NREM stages, the REM component of sleep then follows. This is characterized by dreaming. The REM component intermittently happens at about 90-minute intervals and it dominates about 50% of sleep.

Article Source: http://EzineArticles.com/